This is an extraordinarily complex area. What we can agree on, is that growth hormone peptides are so much more aligned with our body than pure hormone products.
There are two different divisions when it comes to peptides hormones.
GHRH peptides and Ghrelin mimetics.
GHRH is produced from other cell types in the body as well as the hypothalamus.
GHRH affects:
- Cardio protection
- Immune system and inflammation
- Wound healing
- Inhibition of apoptosis and atrophy. (Muscles)
- Reduction of visceral fat, dyslipidemia and markers of cardiovascular risk.
- Reduction of pulmonary permeability and edema. (Lungs)
- Proliferation of normal and cancer cells.
- Endometrium and reproduction system.
- Pancreatic B-cell survival and insulin secretion
GHRH and the brain:
- Many cell types and locations in the brain with GHRH receptors.
Has several positive effects.
Hormone peptides work naturally with our body, the body is responding to them instead of reacting to them.
What is Ghrelin?
Ghrelin is a novel gastric hormone recognized in 1999 as a mediator of growth hormone release.
Newly discovered biological roles of ghrelin imply that it may have other important physiological functions as well.
Given the orexigenic and adipogenic properties of ghrelin, treatment with an antagonist would seem logical in obesity.
Ghrelin receptor (GSH-R)
Mainly expressed in the hypothalamus, present in other part of the brain, muscle, liver and heart.
Potent GH release.
Thymus rejuvenating effect.
Anti-inflammatory
– Reduced production of IL-6, IL-10 and TNFa
Gut
– Reduced inflammation
– Improves intestinalis barrier dysfunction.
Brain
– Modulates dopamine signaling.
– Anti-depressive and anti-anxiety effect
Estrogen appears to be necessary for optimal response.
